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KMID : 0616120070380040334
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Korean Journal of Pharmacognosy
2007 Volume.38 No. 4 p.334 ~ p.338
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Anti-Inflammatory, Analgesic and Hepatoprotective Effect of Semen of Rumex crispus )
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Lee Shin-Suk
Lee Sook-Yeon
Lim Dong-Sool
Kim Dae-Hong
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Abstract
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Roots of Rumex crispus (Rc) (Polygonaceae) has been used as therapeutic agents of acute and chronic cutaneous diseases, cathartics, fever and jaundice in folk medicines. Recently, Seeds of Rc has known as a digestive, an anticancer agent and a remedy of acute hepatitis, among many traditional folk medicines. So far it isn’t reported about pharmacological effects of Rumecis Semen. The present study describes the preliminary evaluations of biological activities, anti-inflammatory activity (AA, Carrageenan) analgesic activity (writhing test), and hepatoprotective activities (CCl4), of its methanol extract, ethyl acetate fraction and butanol fraction. Among them butanol fraction showed the highest activity in analgesic acivity.
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KEYWORD
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Rumex crispus, analgesic activity, anti-inflammatory activities, hepatoprotective activity
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